The following is a plan for managing massive
obstetric hemorrhage, adapted from Bonner.
The word order is useful mnemonic for remembering the basic outline.
ORGANIZATION
1. Call experienced staff (including
Organization
obstetrician and anesthetist).
2. Alert the blood bank and
hematologist.
3. Designate a nurse to record vital
signs, urine output, and fluids and
drugs administered.
4. Place operating theater on standby.
RESUSCITATION
1. Administer oxygen by mask.
2. Place 2 large-bore (14-gauge)
intravenous lines.
3. Take blood for crossmatch of 6 U
PRBCs, and obtain a CBC count,
coagulation screen, urea level,
creatinine value, and electrolyte
status.
4. Begin immediate rapid fluid
replacement with NS or Ringer lactate
solution.
5. Transfuse with PRBCs as available
and appropriate.
DEFECTIVE BLOOD COAGULATION
1. Order coagulation screen
(International Normalized Ratio,
activated partial thromboplastin time)
if fibrinogen, thrombin time, blood
film, and D-dimer results are
abnormal.
2. Give FFP if coagulation test results
are abnormal and sites are oozing.
3. Give cryoprecipitate if abnormal
coagulation test results are not
corrected with FFP and bleeding
continues.
4. Give platelet concentrates if the
platelet count is less than 50 X 109/L
and bleeding continues.
5. Use cryoprecipitate and platelet
concentrates before surgical
intervention.
EVALUATION OF RESPONSE
1. Monitor pulse, blood pressure, blood
gas status, and acid-base status, and
consider monitoring central venous
pressure.
2. Measure urine output using an
indwelling catheter.
3. Order regular CBC counts and
coagulation tests to guide blood
component therapy.
REMEDY The Cause of Bleeding
1. If antepartum, deliver the fetus and
placenta.
2. If postpartum, use oxytocin,
prostaglandin, or ergonovine.
3. Explore and empty the uterine cavity,
and consider uterine packing.
4. Examine the cervix and vagina, ligate
any bleeding vessels, and repair
trauma.
5. Ligate the uterine blood supply (ie,
uterine, ovarian, and/or internal iliac
arteries).
6. Consider arterial embolization.
7. Consider hysterectomy.
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